Marquis (15% w/w ponazuril) Antiprotozoal Oral for Horses
Description
Marquis Antiprotozoal Oral for Horses is the first FDA approved treatment for equine protozoal myeloencephalitis (EPM). Equine protozoal myeloencephalitis (EPM) is a common neurologic disease of horses living in the Americas. EPM is caused by the protozoa Sarcocystis neurona and leads to inflammation of the brain and spinal cord, resulting in various neurological deficits in horses such as abnormal gait, stumbling, falling and an inability to rise. The definitive host of EPM is the opossum, which sheds infective sporocysts of S. neurona that infect horses.
Marquis is an antiprotozoal oral paste approved by the FDA for the treatment of horses with EPM. It contains the active ingredient ponazuril which crosses the blood/brain barrier to reach the central nervous system. Once it has reached the central nervous system, ponazuril works to kill S. neurona to prevent the parasite from causing further damage.
Each mL of sterile aqueous solution contains:
 Key Benefits
- FDA approved treatment for equine protozoal myeloencephalitis (EPM)
- Kills Sarcocystis neurona to prevent further damage to central nervous system
- Contains the active ingredient ponazuril
- Requires a veterinarian’s prescription
- Provided as an oral paste
How It Works
Marquis contains an active ingredient called ponazuril, which fights against several life stages of parasites. It passes the blood/brain barrier, then reaches the horse’s CNS (central nervous system), where it effectively kills parasites.
Indications
MARQUIS (ponazuril) is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona.
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